BDBM50020232 1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one(Irindalone)::CHEMBL73461::Irindalone

SMILES Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2ccccc12

InChI Key InChIKey=GHAMYXPEZSUOCU-XZOQPEGZSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020232   

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020232(1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-p...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020232(1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-p...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020232(1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-p...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed